In this opening opinion piece, Dr. Bhavna Mahadew explores the growing instability of the global trade system, highlighting the weakening of the World Trade Organization’s (WTO) dispute resolution function and its implications for fair, rules-based trade. She argues that as multilateralism falters, the rise of unilateral trade practices and fragmented regional agreements threatens the predictability and inclusivity of global commerce. Drawing on the Indian Ocean Rim Association’s (IORA) commitment to trade and investment facilitation, Dr. Mahadew emphasizes the importance of maintaining a transparent, non-discriminatory system that benefits all — particularly developing nations and small businesses. As IORA member states look to deepen cooperation, her piece calls for renewed leadership from the region to uphold and strengthen multilateral trade as a foundation for sustainable development.